… between DNMT inhibitors and chemotherapeutic drugs make combining epigenetic therapy
and … Moreover, DNMT inhibitors can reverse epidermal growth factor (EGF) receptor (EGFR) …

… cancers. In order to promote the development of a DNA methyltransferase inhibitor as an
anti-tumor … the relationship between DNA methylation and tumor, the anti-tumor mechanism, the …

… (DNMTs) to specific genomic loci to promote DNA methylation [19,20,21]. On the … DNA
methylation and histone modification machinery critical for maintaining the cellular epigenetic …

… undergoing clinical stage investigations in different cancer … of the epigenetic therapy
through the implementation of emerging … DNA methylation is an epigenetic process that can be …

… of DNA methylation by DNMTs and specifically introduces this process in the context of tumor
… Similarly, Vendetti et al. proposed epigenetic treatments that target DNMTs and HDACs in …

… epigenetic agents that target three classes of epigenetic … which several inhibitors of DNA
methyltransferase (DNMT) and … Examples of clinical trials of combined epigenetic therapies and …

… epigenetic treatment in cancer. However, delineating various … Many inhibitors in the form of
epigenetic drugs mostly … including DNA methyltransferase (DNMT) enzyme inhibitors and a …

… the potential to target the global methylation patterns for cancer therapy. In this review, we …
of DNA methylation in cancer. We will review the limited success of targeting DNA methylation …

… in glioblastoma multiforme and triple negative breast cancer (TNBC) are providing … inhibitors
along with DNA methyl transferase inhibitors and histone methyl transferase inhibitors are in …

… epigenetic regulation of OC drug resistance and propose the potential clinical implications
of epigenetic therapies … reversing histone modifications and DNA methylation or by targeting …